preparative chromatographyIt is a chromatographic system for the purpose of separating pure substances, and analytical δchromatography is a chromatographic system for the purpose of analyzing sample component♥ information. Based on their different purposes, p'reparative chromatography has many different characteristics relative to aδnalytical chromatography. The chromatographic modes commo±nly used in preparative chromatography are low pressure, medium pressure, and high pr&essure to cope with the separation of samples of different ty✔pes and different purity requirements, while minimizing costs.

 

Low pressure: Generally speaking, low pressure is suita♥ble for easy separation of compounds, but long separation time can easily €cause decomposition of sensitive compounds.

Medium pressure: Medium pressure generally uses a constant flow pump to provide a constant mobi le phase flow rate, with smaller filler particles, higher resolution, hig♠her pressure tolerance and faster flow rate.

High pressure: high pressure is usually used in the later stage of separa≤tion and preparation, and is applied to samples with difficult separation, and the purity can even♦ reach99.9%.

 

Compared with traditional purification methods (such as distillation and extractio≈n), preparative chromatography is a more effective sep aration method, so it is widely used in the extraction and purification of sample↓s and products. With the increasing demand for higπh-purity components in the fields of synthesis, phytolog≠y, biochemistry and pharmacy, the application field of pr→eparative liquid chromatography is also expanding rapidly. At present, laboratory-grade pr​eparative liquid chromatography is mainly used in the following field✘s:

1.Natural medicine chemistry, Chinese medicine chemistry;

2.Protein purification;

3.purification of drug impurities;

4.Preparation of chiral compounds;

5.Industrial hemp extraction;

6.High purity fish oil extraction

Innovation Tongheng is a high-tech company focusing on li∑quid chromatography separation technology. In the past five years¥, it has been aiming at the separation and purification of active substances in  natural products.20years experience in preparative chromatography,Use5A super chromatography equipment with a number of independent inte​llectual property rights was developed in（SuperChrom ®  preparative chromatographic system）. The equipment can be composed of two columns, five columns, eight columns and other multi coluπmn super chromatography system.(An improved simulated moving bed separation method P>atent No:ZL200810121553.7). Can be selected according to product characteristics and process needs. This equipment fills tφhe domestic blank. already in paclitaxel,10DABCoenzymeQ10Orlistat and industrial hemp extraction are verified in ‍several products. Compared with single column chromatogr‌aphy, super chromatography has the characteristics of high p↕roductivity, high yield and low reagent usage. After five✔ years of research and development, testing and improvement, we have a unique advantage in plant eβxtraction.

MainThere are the following points:

 

1.The whole process uses ethanol water as the mobile phase, w<hich is the food law approved the use of solvents;

 

2.High production efficiency, large sample volume, high product yield.;

 

3.This device can extract all the monomers in cannabinoids accordi ng to customer needs, suchCBD,CBG,CBN,CBCand so on, can be produced according to market demand;

4.Low production costs, from flowers and leaves to products, take broad-spectrum oil removalTHCFor example, the production of a kilogram of broad-spectrum oil is less than 1",000 RMB, and the production of a kilogram of high purity oil is less than 1,000 RMB.CBDLess than 2,000, which is not reached by any equipment company in the world.

 

Innovation Tongheng's super preparation chromatography proc€ess (domestic first, international leading), in the application of high-purity fiγsh oil products, the process advantage is very obvious. We start from7010Fish oil does.97%Above high purityEPA,Cost per kilogram550Yuan (including raw materials, reagents, labor, equipment depreciation), on☆ly the traditional high-pressure preparation chromatography production c¥osts.1/3Left and right.

The advantages of super preparative chromatography ma inly include the following points:

1.Large sample loading, high utilization rate of packing;

2.Part of the reagent internal circulation, reagent us$age is low, less than the traditional process reagent usage.1/2;

3.The yield of the product is high, basically in.95%Left and right;

4.Can do purity99Above, single miscellaneous control in0.2%the following;

5.have diameter1000mmSuper preparative chromatography can verify the relevant process parameters on site.